Friday, February 20, 2009

DISC1 and schizophrenia

A number of different genes have been associated with an increased risk for schizophrenia. One such gene is DISC1. A study of 4,651 people in Finland looked into the links between variations in DISC1 and some of the symptoms of schizophrenia and found that it was linked to social anhedonia - the inability to enjoy social interaction - which is one of the main symptoms of the condition.

Tomppo, Liisa ... [et al] - Association of variants in DISC1 with psychosis-related traits in a large population cohort Archives of General Psychiatry February 2009, 66(2), 134-141

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