A 14-week trial by researchers at the Medical University of South Carolina on 371 male and female alcoholics looked into the effectiveness of the drug topiramate and found that as well as decreasing heavy drinking it also had a number of other health effects. Treatment with the drug was found to lower liver enzymes, cholesterol, body mass index and blood pressure all of which have been associated with heart disease. Topiramate also significantly contributed to a decline in obsessive thoughts and compulsions and led to an improvement in quality of life and a reduction in sleep disturbances. Topiramate is licenced to treat headaches and migraine by the U.S. Food and Drugs Administration but not yet for the treatment of alcoholism.
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