Researchers at the Institute of Psychiatry, King's College London have been looking into abnormalities in the white matter of people's brains and how this can lead to the development of schizophrenia. Professor Philip McGuire and Dr Sophia Frangou used a technique called diffusion tensor imaging to examine the white matter of adolescents and adults with schizophrenia. They found that the adolescents had severe deficits of white matter in the posterior (back) region of the brain; specifically the parietal region. In the older patients the white-matter abnormalities had "migrated" to the front of the brain where they had a dramatic impact on the frontal lobes.
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