Topiramate is a drug currently used to treat seizures and migraines. However, a 14-week study of 371 alcoholics in Virginia, U.S. has found that it could also be useful in treating people with alcohol problems. Compared to a placebo topiramate decreased heavy drinking, lowered liver enzymes, cholesterol, body mass index and blood pressure. Topiramate also led to a decline in obsessive thoughts and compulsions about alcohol and a greater improvement in people's quality of life and a reduction in sleep disturbances.
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