Friday, January 11, 2008

Disappointing results for escitalopram in older depressed people

A study into the effectiveness of escitalopram in treating depression in people over 60 has yielded disappointing results. The 12-week trial divided 264 patients into two groups one receiving escitalopram and the other a placebo. Escitalopram was no more effective at treating depression than a placebo and 11% of the people taking the drug discontinued it due to side effects of headache, nausea, diaorrhea and a dry mouth.

Bose, Anjana, Dayong, Li and Gandhi, Chetan - Escitalopram in the acute treatment of depressed patients aged 60 years or older American Journal of Geriatric Psychiatry January 2008, 16(1), 14-20

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