Research supports the effectiveness of numerous pharmacological and psychosocial interventions for helping individuals with serious mental illness reduce psychiatric symptoms and build more satisfying and productive lives. Treatment non-adherence, however, remains a major obstacle to recovery with between forty and sixty per cent of people with a severe mental illness failing to engage in aftercare treatment. Non-adherence is associated with more serious symptoms, suicidality, violent behaviour, functional limitations, higher relapse rates and hospital recidivism. A team of researchers from Chicago looked at 31 studies into interventions designed to prevent non-adherence to treatment. They found that assertive/intensive case management improved outpatient treatment retention and that behavioural therapy enhanced medication adherence.
Lehner, Renanah K. ... [et al] - Outpatient treatment adherence and serious mental illness : a review of interventions American Journal of Psychiatric Rehabilitation 10(4), 245-274