A review of data from drug trials submitted to the U.S. Food and Drug Administration has found that, compared to a placebo, SSRI antidepressants appear only to help people with very severe depression. The researchers found that placebos were able to duplicate 80% of the improvements achieved by the drugs fluoxetine, venlafaxine, paroxetine and nefazodone.
You can read the full text of this review at
http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050045&ct=1&SESSID=1df302fc7bf05c70bb0c617dd6141e45
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