A team of researchers led by scientists from the School of Medicine at Cardiff University has found two new genes linked to Alzheimer's disease. The team studied 19,000 DNA samples from older adults in Europe and the U.S., 7,000 of whom had Alzheimer's disease. The researchers found that twon genes called APOJ, or clustrin, and PICALM were both linked to Alzheimer's disease. APOJ is found on chromosome 8 and may be involved in the formation of amyloid plaque deposits in the brain characteristic of Alzheimer's. PICALM is on chromosome 11 and is thought to be involved in the breakdown of synapses that link brain cells together.
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