Schizophrenia is one of the most debilitating of the major psychiatric disorders and is also one of the most difficult to treat. Although a number of drugs are available to treat the condition they can cause significant side effects ; many patients experience only a partial improvement in their symptoms while up to 30% experience no relief at all. A study of 444 patients compared those taking a placebo with those taking an existing anti-psychotic drug, olanzapine and those taking a new anti-psychotic drug paliperidone. Although the new drug was found to be no more effective than olanzapine it can be taken in a long-acting, extended-release form and was found to be relatively safe.
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