A review of newer antidepressants published in the Lancet looked at data from 117 studies. It found that sertraline (brand name Zoloft) and escitalopram (Lexapro) were the most effective and well-tolerated. The studies were carried out from 1991 to 2007 and involved more than 25,000 participants; 12 drugs were compared. Mirtazapine (Remeron) and venlafaxine (Effexor) were also more effective than the other drugs. Far more people remained on sertraline and escitalopram than on the other drugs.
You can find out more about this research at
http://uk.reuters.com/article/healthNews/idUKTRE50S00O20090129?feedType=RSS&feedName=healthNews&sp=true
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