People taking antipsychotic drugs can be at an increased risk of developing osteoporosis as the drugs can reduce oestrogen and testosterone. A study of 31 female patients in a high-security hospital looked at which drugs they had been taking and for how long, the women's age, whether they smoked and their weight, then measured the women's bone density. The only variable that was linked to bone density was the women's weight with the chubbier women being less at risk of osteoporosis.
Orr, Jane and Jamieson, Liz - An audit of the association between the use of antipsychotic medication and bone density measurement in female patients within a special (high security) hospital The Journal of Forensic Psychiatry and Psychology 18(3), 317-330
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