Friday, December 12, 2008

Cholinesterase inhibitors for dementia

Researchers at Indiana University School of Medicine looked into the effectiveness of drugs called cholinesterase inhibitors at treating the behavioural and psychological symptoms of dementia. The drugs work by raising the level of a neurotransmitter called acetylcholine in the brain, which assists memory, thought and judgement. The researchers reviewed the results of nine clinical trials of the drugs and found that they led to a statistically-significant reduction in behavioural and psychological symptoms such as aggression, wandering and paranoia. The drugs were found to be safe and produced no side effects in contrast to the antipsychotic drugs that are sometimes used on this group of service users.

You can find out more about this study at

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