Polycystic ovary syndrome (PCOS) is estimated to affect between 5-10% of women of reproductive age and its symptoms include weight problems, lack of regular ovulation and/or menstruation and excessive amounts of androgenic (masculinizing) hormones. While the causes are unknown insulin resistance, diabetes and obesity are all strongly correlated with PCOS. A study of 84 women in Turkey used two common measures, the General Health Questionnaire and the Beck Depression Inventory, to compare levels of mental-health problems in women with and without PCOS. The women with PCOS had significantly higher levels of mental distress than the other women and their levels of mental distress were correlated with their Body Mass Index and their Waist-to-Hip Ratio, i.e. the heavier they were and the larger their waists the worse their mental-health was.
Adali, E. ... [et al] - The relationship between clinico-biochemical characteristics and psychiatric distress in young women with polycystic ovary syndrome The Journal of International Medical Research November/December 2008, 36(6), 1188-1196